SickKids Cancer Sequencing Program
The SickKids Cancer Sequencing Program (KiCS) is a research study at the Hospital for Sick Children (SickKids) designed to learn how to best use a new type of genetic test, called next generation sequencing (NGS) in clinical cancer care. This program is for children who have been diagnosed with a solid tumour or a blood cancer (leukemia or lymphoma).
The test will be used to learn about the genome of a child’s cancer and healthy cells. By doing this, researchers want to know if this new test can help:
Better characterize a child’s tumour and identify its unique genetic fingerprint.
Use this information to identify specific treatment options for a child’s tumour.
Use this information to follow a tumour’s response to treatment.
Gain information about a child’s prognosis.
Understand the cause of a child’s cancer.
Most children with tumours do not yet have this kind of test as part of their regular care.
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This study is being led by Dr. David Malkin and Dr. Adam Shlien at The Hospital for Sick Children (SickKids). The current funder of this research is the Garron Family Cancer Centre. Dr. David Malkin, Dr. Adam Shlien, and the other research team members have no conflict of interest to declare.